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Sunday brings the initial Wear-Tyne derby since 2024, but who will emerge victorious – Sunderland or Newcastle?
"During the bulk of last season, you couldn't have imagined the Wearside club earning promotion and challenging with Eddie Howe's Newcastle, never mind being above them in the table," remarked pundit Chris Sutton.
"Things are very different now, and the way they play makes me think they've got a genuine opportunity."
Sutton is making scoreline guesses for all 380 Premier League games this season, against artificial intelligence, the public and a variety of guests.
For week 16, he faces off against England Gaming star Daniel 'Stingray' Ray.
Ray is vying for victory for the England's esports team – the Football Association's formal esports team – at the EA Sports FC digital Euros finals tournament, which is being held at Twickenham Stadium on Saturday.
The action will be streamed on Uefa's YouTube, Instagram Live and short-form video channels, as well as the official Twitch channel and its YouTube counterpart and England's Twitch.
Do you agree with their forecasts? Feel free to submit your own guesses below.
The fan-favourite scoreline selected for each game is featured in the scoreboards at the foot of this page.
A correct result (selecting a win, draw or defeat) is worth 10 points. A perfect prediction earns 40 points.
Ray, who represents Gen City and the Premier League champions as well as England, is entering the fray at the eEuros finals after successfully navigating the qualifying.
Eight players will represent their nations at the finals in a straight knockout, playing for a substantial cash prize and a coveted spot in the world finals play-offs, with the Danish representative Anders Vejrgang defending the title he won last year.
"My mindset is really good for it," Ray remarked. "I have a really good coach alongside me and preparation has been going well.
"It is invariably an honour to play for your country. Of course when you are younger, you fantasise about doing it as an actual footballer, but when you go into this job and there is an opportunity to represent England, putting the shirt on is something incredible.
"I beat Vejrgang 9-4 in qualifying to get here. I've played against him recently just in practice, and in other tournaments before - but I'd never beaten him in a tournament before.
"I believe he is the best player in the world so beating him in a tournament like this just delivers a huge surge of confidence."
Premier League Weekend Preview
Saturday, 13 December
Chelsea vs Everton
Stamford Bridge, 15:00 GMT
The London club were impressive against the Gunners at the end of November, when they secured a point after going down to 10 men, and I was thinking this is it, they could possibly be challengers for the crown.
In the matches following, however, they were outfought by Leeds, looked lethargic against Bournemouth and this week got turned over by Atalanta in the Champions League.
So head coach Enzo Maresca really needs a win here to return to winning ways, but it is a tough ask because the Toffees are such a dangerous team.
Their key midfielders are playing at the top of their game and Everton have got a bit of momentum at the moment.
On form you would likely back the visitors, while the most prudent prediction would probably be a draw, but I'm going against logic.
Chelsea haven't given me any good cause to back them recently, but I just have a hunch Chelsea will take this one because they are at home and they are due a win.
Sutton's prediction: 2-1
Stingray's prediction: With this being at the Bridge, I am going to back Chelsea. I think they will start off really well and go 2-0 up, then Everton will nick one back but then Chelsea score late. 3-1
AI's prediction: 2-0
Liverpool vs Brighton
Anfield, 15:00 GMT
I'm attending this game and it will be interesting to see what we get from the Reds.
It was great to see for Reds boss Arne Slot to get such a crucial result at Inter Milan on Tuesday following all the discussion with Mohamed Salah this week.
Slot shouldn't need to put up with that distraction. I know Salah has been a great for the club but fundamentally Slot just wants to win games and there is no bias in his team selection.
Liverpool changed their tactical setup against Inter and went with a midfield diamond and two up top.
All the talk is going to be talking about whether Salah is included for this game, but the only way he is going to be reintegrated is if he apologises.
Slot's attention will be on winning this game, but it is a tough one.
It's fair to say it is the same for most teams but I find Brighton so unpredictable. I always feel they have got a goal in them, but they are vulnerable at the back too.
The Merseysiders need to get back to winning consistently, but I am not sure how much their exertions at the San Siro will have taken out of them.
I have whacked a couple of Brighton players in my FPL team, so they will almost certainly blank - but I do fancy them to get something at Anfield.
Sutton's prediction: 2-2
Stingray's prediction: This is a game which is going to give Liverpool a bit more of their confidence back. Obviously they had a good win in midweek and they can build more momentum here. 2-1
AI's prediction: 3-1
Sunday, 14 December
Sunderland vs Newcastle
Stadium of Light, 14:00 GMT
The Wearside club have had the week off while Newcastle had to exert themselves against Bayer Leverkusen on Wednesday, only to let their lead slip away late on.
Apart from their superb performance against Everton a couple of weeks ago, Newcastle's away form has been poor, especially straight after they've played in the Champions League.
The pattern suggests that pattern to continue on Sunday, and their fatigue is likely to be a key element in how this game goes because of their rivals' energetic style.
Their match against Arsenal demonstrated how relentless Regis le Bris's side are. They overpowered the Gunners, and it was amazing to watch.
Many pundits talks about how Granit Xhaka has been brilliant for the Black Cats, and he has been brilliant, but Noah Sadiki, who plays alongside him, has also been one of the top transfers and should be recognised too.
I am expecting this being the best game|most exciting fixture